Publication: When the X chromosome makes the difference: a key mechanism for cell survival

  • Research
Published on January 14, 2026 – Updated on January 14, 2026
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on the January 7, 2026

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In a study published in Current Biology, Bruno Hudry's team (Valrose Biology Institute) shows that dosage compensation, a mechanism that balances the expression of X chromosome genes, is essential for the survival of respiratory stem cells in Drosophila flies. This work, published in December 2025 in Current Biology, reveals the first cellular defects explaining the effects induced by X chromosome monosomy.

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Researcher contact: Bruno Hudry - Valrose Biology Institute (Université Côte d'Azur, CNRS, Inserm)